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By Shera Dalin

Venture capital investors are increasingly seeking alternative energy and other “cleantech” companies, putting St. Louis in a prime position to attract investment, business leaders say.

In fact, the trend toward cleantech and alternative fuels investment is so energized that entrepreneurial showcase InvestMidwest is breaking out a cleantech segment at its annual meeting this coming Feb. 19 through 20 to meet the demand, says Christine Walsh, executive director of InvestMidwest.

“Alternative energy companies that will be considered for this track will include companies that specialize in renewable energy, biofuels, wind energy, solar energy and all related technologies,” she says, adding that the deadline to apply is Nov. 2nd.

Venture capitalists boosted their investment in cleantech by 41 percent to $264 million in the first quarter of this year compared to the fourth quarter of 2006, according to the National Venture Capital Association (NVCA). For 2006, cleantech investments were $1.5 billion, or an average of $383 million per quarter.

“Particularly in biofuels, there are competitive advantages for startups located in our region," explains Jay DeLong, vice president for New Ventures and Capital Formation for the RCGA. “Having early adopters as customers for your technology is critical for startups, and the practicality of environmental technologies should be a plus here.”

To help St. Louis entrepreneurs capitalize on the laser-focus on this segment, the Nidus Center for Scientific Enterprise recently joined the Clean Energy Alliance created by the federal National Renewable Energy Laboratory (NREL) in Golden, Colo. The Alliance, while not necessarily producing funds to help launch startups, will link incubators such as Nidus and their tenants with the considerable resources available at NREL, Nidus President and Chief Executive Bob Calcaterra says.

Membership in the Alliance means assistance with federal grants and the ability to tap into NREL research, he says. At least one local company that could benefit is Akermin Inc., which is developing a fuel cell that runs off of alcohol.

“I’m doing this with the hope that we might be able to attract more companies like that,” Calcaterra says.

“A number of (venture) funds are cropping up around the country whose sole purpose is to grow clean-energy companies. Some venture funds are in their third or fourth fund committed in part to clean fuels.

Part of the excitement behind clean energy is the urge to reduce the U.S. dependence of foreign fuel as well as lessen the greenhouse-gas effects produced by fossil-fuel pollution.

The backbone of St. Louis’ BioBelt venture investment—life science and biotechnology companies—is expected to remain strong. In the first quarter of the year, biotech investment ranked as the No. 1 industry and medical devices was at an all-time high, NVCA reported. Later stage investing also bumped up for the quarter to the highest dollar level since the fourth quarter of 2000.

That’s good news for the medical device entrepreneurs coming out of private industry, as well as Washington and Saint Louis universities, Calcaterra says. He pointed to the increasing attractiveness of technology, such as a new heart defibrillator being developed by Wash U’s Dr. Igor Efivmov and a microscope that can look at living cells in the body under development by Dr. Samuel Wickline, also at Wash U.

“That’s some really exciting stuff,” Calcaterra says. “One of the reasons medical devices are always attractive is that the regulatory hurdles are not as high as with a drug, so it’s an easier hurdle to clear and it’s faster.”

There is also interest at the earliest stage, or angel investment, says Gil Bickel, president of the St. Louis Arch Angels investment network.

“The VCs that we are seeing that are active in the financing market are looking at bio- and agritechnology companies. They don’t seem to have a lot of interest in more traditional types of business, but are much more interested in companies that have substantial intellectual property with a three- to seven-year time horizon.”

Agritechnology is an area ripe for the picking because few VCs are focused on such firms, Calcaterra says.

The principals of the new agritech MidPoint Fund, operated by IN Partners LLC of Indianapolis, toured St. Louis over the summer looking for prospective investors and investment opportunities. Managing partners Ron Meeusen, a former Dow Agrosciences executive, and Andrew Ziolkowski, engineer/physicist and life sciences investor, plan to raise $100 million for MidPoint.

The fund will invest in six types of firms and is investigating several in St. Louis, Meeusen says, declining to name the prospects. The types of companies MidPoint seeks are bioproducts such as fuel and plastics; human nutrition, specialty foods and nutraceuticals; food safety products/processes; animal health and pets; environmental technology such as converting wastes into usable products; and general technologies.

The fund plans to make its first round of investments by the year’s end.

MidPoint is focusing on the Midwest because it has the greatest concentration of food and agritechnology, Meeusen says.

“There’s a wonderful marketplace here in the billions of dollars, but there was virtually no dedicated financing chasing those technologies,” he points out. “There’s a big opportunity and need.”

Similarly, Augury Capital Partners in Clayton is raising between $50 million and $100 million for late-stage investment. Augury, formed in fall 2006, aims to invest in the Midwest, South and Europe. In particular, investments will be focused on the managing partners’ areas of expertise: life sciences and financial-services information technology, particularly electronic payments firms.

The company has already invested in Force10 Networks of San Jose, Calif., an IT networking company with offices in the U.S. and Europe.

“Our fund is focused on providing growth capital, so it is quite late stage. We may invest as much as $10 million in any one company, but it is typically over a short number of rounds of funding, one or two, because of our late-stage investing,” explains David Truetzel, managing partner of Augury with Robert Wetzel.

The partners like the prospects available in the St. Louis area and are both fifth generation St. Louisans, which is why they based the fund here.

“St. Louis has some very good technology in each of our industries and lies in the center of an underserved private capital market in the Midwest, Mid-Atlantic and the South, where there exists significant opportunities in payments and life sciences,” Truetzel says.

Ultimately, the St. Louis region has many of the elements necessary for strong VC investment, Bickel says.

“You have the universities turning out the technology, a very strong entrepreneurial community, mentoring with Innovate St. Louis, the RCGA and capital through Arch Angels,” he says. “You have the perfect storm.”

 

 

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Rodger Riney
Cover Story with Rodger Riney, Scottrade
Dr. Igor Efivmov
Jeff Cooper
Chris Varvares and Joel Prakken

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ConocoPhillips
Earl Wilson Jr.
Earl Wilson Jr.
Bob Wallace
Bob Wallace
Tour of Missouri

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