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21ST CENTURY SCIENCE:
FOUNDATION FOR INNOVATION


By Mark S. Wrighton
Chancellor and Professor of Chemistry,
Washington University in St. Louis


Mark S. Wrighton Chancellor, Washington University in St. Louis

Advances in science and technology have fueled the advance of the United States as the world’s most powerful nation. Today, we face global competition on many fronts, but we in Missouri clearly have an opportunity to enhance our region through innovation and entrepreneurship. Much of this promise stems from advances in science and engineering. President Bush’s American Competitive Initiative calls for an expanded investment in science and engineering education and research. The World is Flat by Thomas Friedman has also re-kindled America’s competitive spirit by detailing the advances of other nations in their development of the use of technology.

Missouri’s assets include institutions engaged in creating new knowledge from which emerge new opportunities to bring benefit to society. Research universities, such as the University of Missouri, Saint Louis University, and Washington University, are engaged in discovery science and knowledge creation. In addition, research institutes like the Stowers Institute in Kansas City and the Donald Danforth Plant Science Center in St. Louis are developing as centers of knowledge creation in the life and plant sciences. Moreover, we are fortunate to have science- and technology-based companies in our state that have a vital stake in the future and are also engaged in knowledge creation that can benefit our society. St. Louis corporations like Pfizer, Monsanto, Mallinckrodt Tyco Healthcare, Boeing, Emerson, and Sigma-Aldrich have exciting research efforts that yield new knowledge of value to their businesses leading to products of economic and social value.

In connection with strengthening our region’s economy, research universities have a far ranging responsibility to rapidly transfer the results of scientific discovery to organizations that can develop and commercialize a technology associated with a scientific breakthrough. At Washington University, our efforts to bring benefits to our community include working with mature, but growing and innovative companies like Pfizer, Monsanto, Emerson, and Boeing. For such companies, it is generally the case that intellectual property created by University researchers and patented by the University can be transferred through licensing agreements to the companies that represent the best prospects for developing and commercializing the research results. But we also work with the community to spawn new companies based on new science that sometimes represent the best path to advancing a technological development of commercial and social importance. Companies like Divergence at the Nidus Center for Scientific Enterprise or Kereos at the Center for Emerging Technologies represent just two examples of exciting new companies contributing to transferring the results of research to benefit society.

INNOVATION STEMS FROM STRONG SCIENCE AND STRONG PEOPLE

Technological innovation comes from strong science and engineering. If such innovation is to grow here, we must work to secure the largest and strongest science and engineering enterprise possible in our universities, research institutes, and in the region’s corporations. In St. Louis, we have major scientific strengths, including plant science and agricultural biotechnology, bioenergy, computer science, human biology, biomedical engineering, genomics and biodefense, just to name a few.

Missouri certainly has much of the infrastructure needed for technological innovation and entrepreneurship, but ultimate success depends on people. It is not always appreciated that advances in science come from the work of people. Often, just a few people, or even single individuals, are associated with a discoveries or innovations that lead to major technological developments. The infrastructure needed and the breadth of opportunities suggests that the region needs many talented people in a wide range of fields—people educated and prepared to become engaged in innovation and entrepreneurial activities. Business leaders, venture capitalists, and lawyers, not just scientists and engineers, are needed. This compelling need for the right people is fulfilled uniquely by research universities. Universities attract talented students, and the graduating students and postdoctoral researchers leave with the “know-how and show-how” necessary to develop new science in to new technologies.

To attract and retain the best people, our region needs the best facilities and equipment along with the commitment to have a high density of the highest-quality people. The best people want to work with other talented people. St. Louis’ warm and welcoming community, its cultural institutions, its low cost of living and high quality of life are large positives in recruiting, but they are all secondary factors in the decision talented people make to come here. For the most outstanding scientists and engineers, facilities, equipment, colleagues and financial resources for research are the major factors in recruiting.

FUNDAMENTAL AND APPLIED RESEARCH: WE NEED BOTH

While it is important to keep an eye on the practical consequences of research and to be able to respond appropriately to a discovery of technological importance, it is also important to support basic research that has no immediate practical application. It was just about a century ago that chemists and physicists were coming to understand the electronic structure of atoms and molecules. Who could have foretold that such understanding would lead to the development of lasers having applications ranging from cash register scanning to cutting tools, eye surgery, and even CD and DVD players? Research in general, and especially research at universities where research and education go hand-in-hand, is not always a straightforward path to a discovery. Indeed, some of the most celebrated discoveries were completely unanticipated and required special creativity on the part of the researcher to be able to realize the importance of what was observed!

The federal government is the largest and most important source of support for research at universities and this investment needs to be enhanced. There is a growing awareness of this imperative. But as fundamental research progresses and predicts the course of applied research, universities and companies often develop research relationships that can bring benefit to both entities. Typically, companies provide the financial resources for a research program and the university provides people and infrastructure for the research. The partnership with a company enhances the educational opportunity for students by acquainting them with key problem areas where scientific breakthroughs can make a difference. In some cases a company wants to support fundamental research to define what is possible, and in other cases the research is applied and directly assists the company on its path to technological development and commercialization. Supporting existing companies and assisting the development of new ones is a compelling responsibility for our research universities and institutes. Universities serve the unique role of preparing people for creative work, and all research activities need them. Encouraging more of our talented graduates to remain in our region is a compelling objective. Exciting opportunities to develop new technologies in corporations will contribute to keeping them, and our efforts to encourage corporate research and development will bring major dividends.

A FUTURE OF ECONOMIC PROSPERITY

If we are to grow and prosper as a community, St. Louis’ business, higher education and research communities must work more effectively with each other. Science and engineering research represents an enormously rewarding investment that has proven to lead to economic prosperity. Economic prosperity is critical to sustaining the region’s strength in cultural and recreational resources, because without profits, our corporations will not be able to provide the philanthropic support needed for exceptionally fine institutions we enjoy in the region. Expanding employment opportunities for all in our region depends on strengthening the region’s competitiveness and innovation. Creating new, high quality jobs in our region will come from new enterprises, many of which can come from advances in science. The creation of a stronger culture of scientific innovation, technology transfer, entrepreneurship and an appreciation for the role of basic research will serve Missouri well. None of this is easy, but all of this is possible. It is time for the “Show Me State” to show its stuff and fulfill its potential as a leading region of innovation and entrepreneurship. Boeing, Pfizer, Monsanto, Emerson, Sigma-Aldrich, and MEMC illustrate well the important role science and technology are already playing in our region and in the world. Our region has much more potential and our future depends on realizing it. Realization of the promise of our region can sustain America’s leadership in innovation and service to society.

 

 

 


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