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Above:The Donald Danforth Plant Science Center is one of the world’s largest and most advanced research facilities devoted to basic plant science research.

Growing Plant and Life Science

The state-of-the-art Donald Danforth Plant Science Center recently opened to great expectations.


By Peter Downs

It “will have global significance in the best possible cause: to feed the world,” says former United States Senator John Danforth, chairman of the Danforth Foundation that helped fund the center. It is also “crucial to the future of this region,” he adds.

“The Donald Danforth Plant Science Center will ensure that Missouri is at the center of this century’s revolution,” says Sen. Christopher “Kit” Bond. “It will draw high-paying jobs and talent to the region.”

Robert Calcaterra, chief executive of the Nidus Center for Scientific Enterprise, calls the new Donald Danforth Plant Science Center the foundation of efforts to make metropolitan St. Louis one of the top locations in the world for life sciences, the center of the BioBelt. He expects research at the center will yield commercial products, and start-up companies to make them, that in coming years will help drive the region’s economy forward.

Hendrik Verfaillie, president and chief executive officer of Monsanto Company, agrees, and says it will benefit established St. Louis companies, too. “The Danforth Plant Science Center is a catalyst for St. Louis becoming the Silicon Valley of life sciences to feed population and create entire new uses for crop plants. It will help attract global talent to St. Louis, which companies like Monsanto need.”

Of course, St. Louis was already a major center of life sciences, says William Danforth, chairman of the board of trustees of the Danforth Plant Sciences Center, but to become a leader, “we needed a building.”

That’s a lot of weight to put on a building, but this one bears it grandly. Its architectural design is recognized as having the potential to contribute at a high level to the success of the center as a research facility and as a visible international symbol for excellence in this field.

The laboratory space consists of 15 flexible/open plant biotechnology laboratories with associated support spaces with flexible fit outs. All tissue culture and Biosafety areas are consolidated in a single lab. Bioinformatics laboratories include the largest computer array dedicated to plant biology in the world: 1,040 linked Pentium III processors. The 15,000-square-foot greenhouse includes 14 rooms and a work area, including two air-conditioned areas. The head house, which supports the greenhouse, includes 19 walk-in plant growth rooms, 38 reach-in plant growth chambers and a soil mixing area. The Center’s research space also includes suites for x-ray crystallography, mass spectrometry and electron microscopy.

The environmentally-controlled growth rooms and growth chambers, the likes of which are found nowhere else in the U.S., are equipped with a unique lighting system that, for the first time, allows researchers in the U.S. to accurately control the amount of light plants receive, which will help determine how modified plants will fare in different climates.

A prestigious research center is more than laboratories, however. The design must encourage communication and collaboration between scientists in different laboratories. To help recruit scientists from around the world it must be welcoming to people from different cultures, and it must reflect the elegance and sophistication that are a hallmark of aspirations to be the best.


The Danforth Center does all of that. A three-story atrium provides a dramatic, sunlit, plant filled central circulation and casual meeting center. This space opens at the building front to a sun-screened south facing lobby/exhibition space, which displays the scientists’ work at the center and worldwide. The rear of the atrium opens to a planted roof deck overlooking the greenhouses and the 40-acre site. A separate chemical storage building and site and building maintenance facility are provided adjacent to the building.

These informal meeting spaces encourage communication, collaboration, and creativity including seating areas in the atrium and on the roof deck, a faculty lounge, a library, conference and coffee bar spaces on each of the four floors, and the open, flexible seating areas in the dining/prefunction space, adjacent to the 302-seat auditorium and the dining area. A story-high fountain and water wall provides sound masking and focus for this large space.

Ultimately, the $75 million research center will house 17 principal investigators—currently it has 11—and more than 200 scientists, technicians, post-doctoral researchers and graduate students, making it one of the world’s largest and most advanced research facilities devoted to basic plant science research.

A World-Class Research Faciity
The innovative Donald Danforth Plant Science Center is a building of international significance, both in its mission and its design, and the design reflects the mission.

The Danforth Plant Science Center is a collaborative project to combine science and nature for the benefit of the international community—to better understand plant biology in order to improve the nutrition and health of the world’s people in a way that sustains the environment.

According to the London, England-based design architects Nicholas Grimshaw & Partners Limited, the combination of natural building elements such as terra cotta with technological elements like machined aluminum reflects the mission of having science complement nature. The international design competition to select a design architect, and the use of building materials from around the world, reflect the Center’s international orientation. And the design of the facility’s research spaces and services to encourage informal communication and interaction between researchers reflects the social and collaborative nature of scientific research, says Mark Husser, project director for the technical architect, HOK.

Unlike many research facilities, this one is meant to be open to the public, with educational spaces for introducing the public to the research through slide presentations and lectures.

The central atrium is a fully accessible, three-story high public space enclosed by a sky lit roof and glass walls on either end to create a light and airy internal garden. It stands above the ground and basement levels in order to maintain public access to the main space while special events are taking place in the conference rooms or auditorium below. Environmental sustainability—and energy conservation—are reflected in the decision to not fully air-condition the atrium. This provides a balance between the fully air-conditioned lab areas and the outside environment while reducing the operating costs of the building.

By its very nature, a plant science research facility uses much more energy than a typical office building. The heating, ventilation, and air-conditioning (HVAC) system, for example, uses 100 percent outside air—the typical office building uses 20 to 30 percent fresh air, says Ray Myers, project director for the construction manager McCarthy Building Companies—so it doesn’t contaminate experiments in one lab with airborne particles from another lab. That forces the HVAC equipment to use more energy to heat building air in the winter and cool it in the summer than it would for an office building. This facility, however, also has a heat recovery system, says Michael Bieg, president of Icon Mechanical, one of the mechanical contractors during construction of the facility. That system captures thermal energy from exhaust air and uses it to help heat, or cool, as necessary, outside air before sending it through the building.

Guarding against the cross contamination of experiments also means HVAC equipment has to be bigger than in most buildings. “The [HVAC] design is based on 16 air changes in occupied space every hour...where the typical building has only five-to-six changes,” Myers says. The Danforth Center HVAC system uses three chillers, two 750-ton units for the main 150,000-square-foot building, and a 200-ton unit for the growth chambers and greenhouse complex, all linked together in a loop to provide redundancy if one unit should fail or is shutdown for maintenance.



Above: Zhihong Zhang, a scientist in the laboratory of Danforth Center.

In terms of the electrical service, Gordon Kummer, assistant vice president of Sachs Electric, says the building takes five megawatts to power, about twice what is required for a similarly-sized Highway 40 office building. To insure against power outages, the electrical system includes a backup diesel generator with a 5,000 gallon fuel tank that can be refueled while it is running to provide a continuous source of power.

One of the signature features of the building is the huge sunshade with motorized louvers on the south facade or Olive Street side of the building. The design calls for eventually enclosing that space to form a three-story high rise soleil with motorized louvers on the bottom matching those on the roof. The louvers, powered by photovoltaic cells, will open to allow hot air to rise out of the top while drawing cooler air in through the bottom, turning the space into a solar chimney that helps cool the building.

Another of the building’s innovative features serves several functions. The terra cotta and aluminum exterior is really a rain-screen curtain wall with integral sunshading louvers. It tempers the effects of weather on the building envelope, while also, in Myers’ words, giving the building “more of a European flavor.” Terra cotta, he says, though rarely used in the U.S., is used widely in Europe. It is also, according to the architect, an “expressive cladding system that demonstrates the meeting of technology and nature, which is the essence of the Donald Danforth Plant Science Center.”

“We have a global perspective and we wanted to reflect that in the design and function of the building,” says Sam Fiorello, senior vice president, administration and finance, for the Danforth Center.

“Plant science is important to feed the world’s growing population in a sustainable way, without polluting the water and sacrificing topsoil,” explains William Danforth. “The benefits will be better diet, better health, protection of the environment, social stability, and a strengthening of the science base and economy of the region.”

This building, says Roger Beachy, president of the Danforth Center, “will help make the Donald Danforth Plant Science Center a go-to site for research about food, health and nutrition.”



Above: Danforth Center researchers (left to right:) Nicole Kokora, Chellapan Padmanabhan, Jitender Yadav and Ben Fofana discussing their work. The Center’s greenhouse complex is in the background.


Peter Downs is a free-lance writer and editor of Construction News & Review.
 

 

 


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