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By Christine imbs

People are living longer and healthier lives today thanks in part to advances in medical technology. But exactly how does scientific research become mainstream medical care? For many St. Louis start-up companies based in new technology, the answer lies at the area's nationally recognized campus of innovationÑthe Center for Emerging Technologies (CET).

CET opened its doors in Midtown St. Louis in 1998 with the goal of helping young start-up companies develop technological breakthroughs with commercial potential. Marcia Mellitz, president and founder of CET, says creating the Center was a vital step not only in the development of these companies, but of St. Louis as a biotech contender.

"We are incredibly lucky to have one of the top medical schools in the country and one of the top NIH-funded academic medical centers in Washington University," she explains. "And certainly Saint Louis University and UM-St. Louis has some very noteworthy areas of research that they're doing on an international level. But without a place to continue development of that research, preferably on the doorstep where that research originated, there's a good chance that companies won't be created out of these technologies. Either that or they just won't be created here. So this is a very important piece of the puzzle."

CET works with the region's public-private-university partnerships to create the infrastructure needed to nurture and grow these companies. This not only includes an actual space for them to work in that's customized to meet their needs, but assistance with growing their company, developing their technology to become market ready, creating strategic alliances, and raising the tens of millions in funds they will need.

"We do prefer medical companies here, but they don't necessarily have to be medical," Mellitz comments. "What we want is someone who is actually doing research and development that's a proprietary technology. It must be patented or they must have applied for a patent. And, of course, the technology has to be breakthrough."

Currently, CET operates a two-building complex totaling 92,000 square feet designed to support life science and other research companies with a range of laboratories. However they plan to build a new 60,000-square-foot building in which they hope to have 60 percent wet labs and other specialized core facilities. It's something Mellitz says is sorely needed in the St. Louis area.

"We find that there isn't a lot of space to lease in this community if you need wet labs," she explains. "And companies still at the stage where they are living off venture capital aren't exactly considered bankable. So they can't borrow money to set up lab space. The banks will support us because they understand our model and we've been successful. The other part of it is that we have a lot of public subsidy in our facilities. So when a bank loans us money, theyÕre not the only money in the deal."

Over the past ten years, CET has been a major contributor to the growth of the St. Louis economy as well as the development of Midtown St. Louis.

"When we first came to the Midtown area it was a bunch of old warehouses. But once we showed that you could successfully develop advanced technology companies that attract high quality employees, then it made it more realistic to move ahead with the whole idea of the CORTEX district here," Mellitz says.

The Center of Research, Technology, and Entrepreneurial Expertise, or CORTEX, is a life science research and development district developed through a collaboration between Washington University, Saint Louis University, the Barnes-Jewish Hospital Foundation, the University of Missouri-St. Louis, the Missouri Botanical Garden, the City of St. Louis, RCGA, and Civic Progress. So far, CORTEX has attracted over $100 million in real estate investment, including the new headquarters of Solae Company. WhatÕs more, it serves as a magnet for life science companies to relocate to St. Louis.

"So we're helping to revitalize the Midtown area and we're helping create new companies and new jobs. But that's only one piece of this," Mellitz comments. "These are high-growth companies. And because of the kind of resources that it takes to develop their kinds of technology, they are huge wealth attractors."

While housed under CET's roof, tenant companies have attracted over $600 million in funding. If you include graduates of CET, that amount rises to about $900 million. And for the most part that money came from outside the St. Louis region.

"So there is a huge economic impact of well over a billion dollars in the community from these companies," Mellitz says. "And with our new building we stand to double the number of these companies, particularly the medical companies. That's why we're moving ahead with it. It would be a shame for the community if these companies weren't created because we lacked the appropriate space to house them. So this is absolutely critical to the development of industry here."

Currently, 13 of the 16 tenant companies at CET are life science companies and three are IT/engineering companies. Of the life science companies, eight are involved with diagnostics, two are focused on process improvement in pharmaceutical manufacturing, one is in cattle tracking, one uses viruses to destroy cancer tumors, and one is a surgical instrument company. And of the ten companies focused on human health, six are working in cancer, four in heart disease, three in diabetes, and one in Alzheimer's.

"These are the people who are going to help cure major diseases," says Michele Rutledge, CET vice president for resource development. "It's phenomenal. And it's great from a strategic standpoint in terms of the linkage of the leading research universities and medical schools. So it's an exciting time for medical advances in St. Louis. And CET is right in the middle of it all."

 

 

 


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