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FOUNDED BY ENTREPRENEURS - FERTILE FOR ENTREPRENEURSHIP

St. Louis Ripe for Inventors of Ice-Cream Cones, Shoes, Biomed Devices, Just to Name a Few

By Bill Beggs Jr.

Today in St. Louis you can get there from here via Lindbergh Boulevard and Chouteau Avenue, perhaps to party on Laclede’s Landing near the Eads Bridge.

A few tomorrows from now, our region’s highways, byways and places of note could include the Nathan Lakey National Laboratories, Joe Edwards Expressway and the Maxine Clark Memorial Mississippi River Bridge & Entertainment Complex.

In the previous paragraphs we dropped the names of seven men and women who, to a greater or lesser degree, have been responsible for shaping the unique region in which we live, work and play. That doesn’t include our town’s namesake King Louis IX, who arguably didn’t pull himself up by his own bootstraps.

Pierre Laclède and Auguste Chouteau probably could have made the footwear their bootstraps were attached to all by themselves. These men have been immortalized by having scores of things named after them, notwithstanding the generations of St. Louisans to have mispronounced their French names.

We invited a half-dozen historians, business leaders and educators to suggest entrepreneurs who have helped shape the fortunes of the Gateway City since its 18th-century origins as a fur-trading outpost at the confluence of the Mississippi, Missouri and Illinois Rivers. They included: Robert Archibald, president, Missouri Historical Society; Ken Harrington, managing director, Skandalaris Center, Washington University; Tom Melzer, managing director, RiverVest Venture Partners; Walter Metcalfe, partner, Bryan Cave; Kevin A. Schulte, SLU’s Center for Entrepreneurs; and Scott Zajac, managing director, Advantage Capital Partners.

Their input will flesh out the names of a few dozen city fathers (and mothers) who have brought us this far, as well as provide character sketches of the wünderkind who are developing lifesaving pharmaceuticals, engineering entertainment concepts and creating a new social consciousness.

St. Louis Entrepreneurs of Yesterday, Today—and Tomorrow

Not quite 250 years ago, our fair city was founded by entrepreneurs—fur traders who believed the site near the mouth of the Missouri would be ideal to build an international commercial empire.

“A lot of early American communities were founded on a religious basis,” points out Robert Archibald, Ph.D., president of the Missouri Historical Society. “St. Louis was founded for commercial and entrepreneurial purposes. In those days, many believed that geography determined destiny. Rivers were the superhighways of the continent.”

(Editor’s Note: Obviously, we haven’t the room for each and every present or former captain of industry; not to worry, as they’ve all been in these pages many times before, and will be again. By the same token, there are more IT and biotech startups—not to mention dot.coms—than you could shake a virtual stick at. We give many of these ink in our monthly “Tech Talk” column. See page 50.)

St. Louis Entrepreneurs of Yesterday, Today—and Tomorrow

1700

Pierre Laclède

• French-born Pierre Laclède Liguest arrived in New Orleans in 1755, venturing up the Mississippi eight years later to build a trading post after his firm won trading rights in the upper Louisiana Territory. Choosing a site near the mouth of the Missouri, he sent his stepson, Auguste Chouteau, to start the settlement in February 1764. Naming it St. Louis, Laclède laid out streets, made property assignments and governed until territorial officials arrived in October 1765. Laclède, who brought his library to the wild, owned the town’s first industry, a water-powered mill. Archibald emphasizes that it was no mean feat for St. Louis’ first citizen to get furs from the region’s Indian tribes to their ultimate consumers in Europe. As an entrepreneur, “Laclède had tremendous prescience,” says Archibald. (Archibald pronounces the second syllable of Laclède like “bled,” not “bleed.”)

Auguste Chouteau

• It’s a good thing Chouteau wasn’t required to get a work permit. As Laclède’s 14-year-old clerk and lieutenant, Chouteau led the workers who began building St. Louis on Feb. 15, 1764. As the village grew into a commercial hub, he adapted from French to Spanish rule in 1770, then U.S. control in 1804, diversifying into banking and real estate as the fur trade declined. An early historian wrote, “Laclède founded, and Auguste Chouteau built, St. Louis.” Married to a Native American woman, he was as comfortable in the wild as he was in high society. Today’s businessman jetting from St. Louis to Singapore has nothing on Chouteau, notes Archibald. “He understood the 18th century version of a global economy. He worked for kings, queens and Democrats, and got rich at every turn.” (He pronounces the first syllable of Chouteau like “shoe,” not “show.”)

1800

James Buchanan Eads

• A self-educated genius, Eads invented the diving bell in 1842, at age 22. Exploring the river bottom within an air bubble trapped underneath the bell, he gained an understanding of river currents and the forces his namesake Mississippi River bridge would withstand. An entrepreneur’s entrepreneur, Eads convinced none other than Andrew Carnegie to manufacture steel of a specific tensile strength to build his bridge—although Eads had never built a bridge before. When the Civil War began, he conceived of a fleet of armored riverboats, persuaded the Navy of its necessity, then built the boats that captured Forts Henry and Donelson in February 1862—the Union’s first victories. His final engineering marvel was the jetty system that opened the mouth of the Mississippi to seagoing ships at New Orleans. •

Adolphus Busch

• Busch, second-youngest of 22 children, came to the United States in 1857 and started working as a clerk on the riverfront and in the wholesale supply business. Two years later, with his father’s inheritance, he formed a partnership in a brewers’ supply business, but it was his second one, with Eberhard Anheuser in 1866, that made his name familiar throughout the world. Anheuser-Busch’s success was attributable to Adolphus’ organizing genius and imagination—not to mention foresight. He quickly recognized the value of technological advances, adopting refrigerated rail cars and pasteurizing A-B’s brew, but it was his marketing acumen that built Budweiser into the “King of Beers.” He was wealthy as royalty but benevolent, notably as one of the largest contributors to Washington University. Busch Hall, for whose construction he donated $110,000 in 1900, is one of the original buildings on campus. When “Prince” Adolphus passed away in 1913, it made headlines around the world.•

Susan Blow

• The average poor child in 1860s St. Louis completed three years of school before being forced to begin work at age 10. Susan Elizabeth Blow addressed that problem by offering education to children earlier. In 1873, Blow opened the United States’ first successful public kindergarten at St. Louis’ Des Peres School. Blow taught children in the morning and teachers in the afternoon. By 1883 every St. Louis public school had a kindergarten, making the city a model for the nation—and Blow’s tireless efforts for her city and its young people a model for civic-minded entrepreneurs everywhere. •

Theodore Link

• German-born architect Theodore Link came to St. Louis in 1873. He designed more than 100 buildings, including his home at 5900 West Cabanne Place, mansions at 29 and 38 Portland Place, and Grace Methodist Church on Skinker Boulevard. Link’s crowning achievement was St. Louis Union Station. This architectural jewel, completed in 1894, was the largest station of its time. A leader of the Romanesque Revival movement, Link was the first to use electric light decoratively. •

William H. Danforth

• “Danforth” is much easier to pronounce than “indomitable,” but the word and the spirit of entrepreneurship are inseparable. In 1894 Danforth founded the Robinson-Danforth Commission mill to feed the nation’s farm animals. After a hurricane leveled it a year later, Danforth borrowed $10,000 to rebuild. Danforth expanded to consumer cereals in 1898, when he introduced Purina Wheat. In 1902, the same year the company claimed a million homes enjoyed its cereal, the Robinson-Danforth Commission became Ralston Purina. In 1927, Danforth established a foundation to aid educational institutions nationwide. Today the private Danforth Foundation is the region’s largest, supporting numerous civic and educational efforts. Danforth’s legacy has continued through grandsons John and William, one a former U.S. Senator, the other a former Washington University chancellor—and still-vigorous champion of commercializing the life sciences. •

Robert S. Brookings

• Brookings was a phenom who dropped out of school at 16 and made his first million by age 30, selling brooms and other household goods for Cupples and Marston. With partner Samuel Cupples, Brookings developed the Cupples Station complex in 1891. Covering 30 acres, this group of 23 seven-story buildings was a giant freight depot where most of the city’s heavy wholesale trade, amounting to more than $200 million annually in 1900, was handled. Perhaps a more-permanent, less-controversial legacy of this self-educated businessman is Washington University, which had fewer than 100 students when he came aboard in 1895. Using his personal fortune of $5 million, Brookings became president of the board of directors, on which he served for 37 years, helping construct new facilities and lifting the medical school from relative mediocrity to national excellence. Wash U.’s Brookings Hall bears his name. •

1900

Edgar Monsanto Queeny

• Monsanto Chemical Works was founded by Queeny’s father, John F. Queeny, in 1901. But it was his son Edgar who built the foundation of the global corporation that exists today. The elder Queeny, a wholesale drug purchasing agent, invested $1,500 of his own money and borrowed another $3,500 from a local Epsom salts maker to manufacture saccharin, a synthetic sweetener then produced only in Germany. (Monsanto was his wife’s maiden name.) In 1928, Edgar, age 30, took the reins from his ailing father, whereupon Monsanto really took off. Within a year, the company listed on the New York Stock Exchange. Expanding the company from saccharin producer to chemical giant, Edgar saw the company’s sales grow from $9 million in 1918 to $1 billion by his retirement in 1962. His legacy continues with Queeny Tower at Barnes-Jewish Hospital and Queeny Park in west St. Louis County. •

Ernest Hamwi

• Hamwi’s waffle booth at the 1904 St. Louis Worlds Fair was next to that of an ice cream vendor who ran short of dishes. Hamwi rolled a waffle to contain ice cream and the cone was born. Like many entrepreneurs, Hamwi made sure he seized the moment—and the concept—ensuring his immortality. This didn’t happen overnight—Hamwi was issued U.S. patent No. 1,342,045 on June 1, 1920. •

Annie Malone

• A black businesswoman, inventor and philanthropist during the early 20th century, Malone manufactured a line of beauty products for black women and created a unique distribution system that helped thousands gain economic independence and self-respect. She was committed to community building and social welfare. In 1918 she built Poro College, a complex that included her business office, manufacturing operation and training center as well as facilities for civic, religious and social functions. •

Charles Lindbergh

• Lindbergh was chief pilot for the first St. Louis-to-Chicago airmail route. While based at Lambert Field, he conceived of an airplane that could fly from New York to Paris, and persuaded a group of St. Louis chamber of commerce leaders to finance the project. The result was the immortal “Spirit of St. Louis,” which he flew across the Atlantic on May 20-21, 1927. The feat made Lindbergh a national hero, and raised international awareness of aviation’s potential. •

Irma Rombauer

• Renowned as one of the city’s most charming hostesses, Rombauer risked her own funds to publish The Joy of Cooking in 1931. As the Great Depression forced more American families to cook for themselves, Rombauer’s wit and common sense made the chore more pleasurable, and her engaging tone put amateurs at ease. With the 1943 edition, this comprehensible, comprehensive and fun volume became the nation’s most popular cookbook; later revisions, including those by her heirs, continue to meet changing tastes. •

Gyo Obata

• Founded in 1955, Hellmuth, Obata & Kassabaum’s influence on the St. Louis skyline is profound. HOK projects here include Priory Chapel, Boatmen’s Tower, Cervantes Convention Center & Stadium, Forsythe Plaza, Metropolitan Square, One Bell Center, the Children’s Zoo and Living World, and the Union Station renovation. The National Air and Space Museum, the airport and university in Riyadh, Saudi Arabia, and the Taipei World Trade Center exemplify Obata’s work worldwide. •

Joe Edwards

• Not long after Edwards opened Blueberry Hill in the deteriorating Delmar Loop in the early 1970s, he was affectionately dubbed “mayor” of University City. Edwards is largely responsible for helping Delmar make its dramatic loop back to solvency—and incomparable hipness. The Pageant concert hall has helped draw development east of Skinker. The area’s Boho ambience and mix of boutiques, entertainment and restaurants lend a New York state of mind you can’t find anywhere closer than, well, the Washington Avenue loft district downtown. •

Mary Engelbreit

• Engelbreit, who just turned 55 on June 5, sold her first greeting cards to a local store while attending Visitation Academy. Inspired by art from the 1920s and 1930s, she developed a style marked by colorful, richly detailed drawings and short phrases that are by turns whimsical or profound. Greeting cards proved the perfect medium for her work, and after initial successes, she founded her own company in 1983. By 2000 she oversaw a “vast empire of cuteness” that included 12 retail stores, a national magazine and more than 6,000 licensed products. •

David Steward

• Steward founded World Wide Technology Inc. in 1990 with Jim Kavanaugh, posting $812,000 in sales that year. Fifteen years later, the company had grown to 1,100 employees, with sales of $1.8 billion. WWT is a systems integrator providing technology and supply chain solutions. The privately held MBE (Minority-Owned, Small Business Enterprise) owns more than 1.6 million square feet of warehousing, distribution and integration space strategically located in 30-some U.S. cities and South Korea. •

Maxine Clark

• Clark’s brainstorm when shopping for Beanie Babies with a 10-year-old friend in 1996 was the impetus for Build-A-Bear Workshops. For anyone who’s been under a rock the past 10 years, at a Build-A-Bear store customers create their own personalized teddy bears—and other stuffed animals—from start to finish. A hands-on process allows the customer to pick the bear, stuff it and give it a heart and a name. Clark is known as “Chief Executive Bear” at a company whose sense of whimsy goes as far as executives’ answering-machine messages, which wish callers a “beary” nice day. The company boasts 176-plus stores in North America, plus a number of franchises overseas. •

Nathan Lakey

• Lakey was no slouch before joining Orion Genomics, where he serves as president and CEO. He cut his teeth developing new DNA sequencing technologies for the Human Genome Project at Harvard Medical School. Orion, based at the Center for Emerging Technologies incubator in midtown, is pioneering a method for early cancer detection and improved treatment, focusing on cancers of the lung, breast and ovaries. Orion aims to identify tumor DNA and develop diagnostic tests to detect even minuscule amounts in a patient’s blood, enabling early detection, when cancer is most treatable. Initially founded in 1998 as an agricultural biotech company, Orion maintains a division that concentrates on mapping the genes of plants. •

2000

Bob Butler

• In 2002, Butler received two gift cards for retailers he didn’t patronize. When he found that eBay was the only place he could sell them, Butler realized an untapped market existed among folks who didn’t need or want cards they received. Lots of folks: At the holidays, Americans buy nearly $20 billion of the things in lieu of selecting the wrong gift. Butler approached several potential investors who wouldn’t pony up because nobody was doing anything similar. That, Butler insisted, was precisely the point, whereupon he found the seed money to launch CardAvenue.com in 2004. Butler is CEO of the website, which charges a 6.25 percent fee from the seller and a 50-cent closing fee only if a sale or trade is completed. If the card doesn’t attract a new owner, the seller isn’t out any money. Like many entrepreneurs, Butler also has a “real” job—he’s an insurance broker with The Daniel & Henry Co. •

Theresa Wilson

• Visitors to BlessingBasket.org, which Wilson founded just three years ago, have put the U.S. equivalent of well over $1 million directly into the hands of the world’s impoverished, according to the website. Buyers can purchase baskets from weavers around the world who receive multiple times more than Fair Trade wages for their baskets—and certainly much more than they would receive in their native countries, including Bangladesh, Ghana, Indonesia and Uganda. •

Dennis Wahr, M.D.

• Wahr practiced interventional cardiology for 15 years, then started a medical device company, Velocimed, with three of his own product ideas. In less than five years, all three products were approved in Europe, one here, and the other two were in clinical trials or about to begin. St. Jude Medical made a pre-emptive bid for Velocimed, whereupon Wahr joined RiverVest Venture Partners here, which had invested in Velocimed’s last two fundraising rounds. Wearing his RiverVest hat, Wahr is co-founding a new company with a Minneapolis inventor. •

Stephen Foster

• Foster, who was born deaf, founded iMAT (iMobile Access Technologies), a startup that brings real-time radio to the eyes of the deaf and hearing-impaired. iMAT invented a device and has developed a delivery service that provides captioned radio content by subscription, thereby enabling broadcasters to reach an unserved market. In doing so, iMAT is working toward the creation of multiple revenue streams through subscription and advertising, expanding radio’s consumer base. What’s more, theaters and stadiums could adopt the technology to serve the 28 million Americans who have some level of profound hearing loss—a population that by 2030 could reach 56 million as baby boomers age. A $20,000 winner of the 2005 Olin Cup entrepreneurial competition at Washington University, iMAT is housed at the Technology Entrepreneur Center, the IT incubator downtown. •

Where Do We Go From Here?


Entrepreneurship is alive and well in St. Louis. But many men and women with great ideas need “block and tackle” skills to move these ideas out of their heads and into other people’s hands. Attorneys to help with incorporation, with patents. Investors willing to shoulder some of the responsibility, and risk. Some start-ups require an incubator environment.

Regardless of the business model, whether bricks and mortar, virtual or both, money isn’t everything for the entrepreneur—it’s the only thing. Practically.

Angel investors are key, says Kevin A. Schulte of the Center for Entrepreneurs at Saint Louis University. St. Louis could build a network of them, he says, if only one percent of the populace stepped up to the plate. Nationwide, he says, that’s the percentage of citizens who are millionaires, or wealthier. If the region has a population of 2.3 million, that’s 23,000 millionaires. Schulte contemplates what the future could hold were each of those people (you know who you are) to commit 10 percent toward building an angel investor network. The pool of money would be so vast that—well, do the math.

“We’d have plenty of money to build a region of entrepreneurs,” Schulte says.

Indeed, prospects are bright.

 

 

 

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Dave Checketts
Scott Zajac
Pierre Laclède
300-foot mural along the Riverfront Trail in North St. Louis

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U City search light
Kelly Ryan
Tim Foley, Erato
Suttle Mindlin

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