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As the head of Mid-America Transplant Services (MTS) sees it, the organ transplant economy is a victim of its own success.

Medical advances in recent years have produced more and more transplant candidates, creating a demand curve that just grows higher and higher each year. But, unlike most businesses that can expand production to meet demand, MTS and other organ clearinghouses around the country must make do with an organ supply that remains stubbornly static. And the imbalance between supply and demand can be downright cruel.

“Despite advances in modern medicine and, ironically, largely because of those advances, the odds of someone dying on the organ waiting list are greater than they were 15 years ago,” says Dean F. Kappel, president and CEO of MTS, a not-for-profit organization that coordinates the procurement of vital organs, tissues and eyes throughout eastern and southern Missouri, southern Illinois and northeastern Arkansas.

Kappel, who commands a staff of 70 employees who call on 120 hospitals within the sprawling MTS service area, explains that a combination of longer life expectancies, improved transplant technology, and better anti-rejection drugs have combined to greatly increase the pool of transplant candidates.



"Despite advances in modern medicine and, ironically, largely because of those advances, the odds of someone dying on the organ waiting list are greater than they were 15 years ago.”
Dean F. Kappel
president and CEO
MTS

In the case of heart transplants, for instance, Kappel says that people older than 50 or 55 were 10 years ago never considered for new hearts. Nowadays, heart transplants are routinely performed on people into their 60s, he says. That means more and more people with bad tickers are waiting for new hearts or, in many cases, new heart valves.

And it can be a long wait. While organ supplies—most notably the heart, liver and kidneys but also lungs, pancreas, skin, bones, bone marrow, and corneas—have never equaled demand, the transplant gap just gets worse. While 14,000 patients across the country were awaiting transplantation in 1998, more than 80,000 are on waiting lists (about 1,700 in the St. Louis region) today. The grim reality is that more than 5,000 people die each year while waiting for an organ.

In the region served by MTS, the number of organ donors has actually dropped since a record of 124 donors in 1998. MTS processed 107 donors in 2001 and won’t reach 100 for 2002, Kappel says.

“Anything that we can do to increase supply would be beneficial,” Kappel pleads.



“Our best hope, though, is that we continue with broad public education beginning at the elementary and high school level and continuing through all phases of adult life.”

Martin D. Jendrisak
transplant surgeon,
Washington University School of Medicine

One thing that might increase supply is to compensate families for organ donations, maintains Ronald Munson, a professor of science and medicine philosophy at the University of Missouri—St. Louis. Munson, author of Raising the Dead: Organ Transplants, Ethics and Society, says he supports a system of compensation within a regulated market.

“It’s not in the best interests of anyone to have organs sold on e-Bay,” Munson says. “My own view is that there is some degree of hypocrisy in passing legislation in our country where we don’t provide people with the funds they may need to pay for an organ transplant while keeping them from selling another organ to pay for it.”

The legislation referred to by Munson is the 1984 National Organ Transplant Act that made selling organs illegal in the U.S. while creating the Organ Procurement and Transplantation Network, including MTS, to equitably distribute organs among transplant patients. Before the legislation, organs were sometimes sold to the highest bidder, according to 1998 congressional testimony of then-U.S. Health and Human Services Director Donna E. Shalala.

Munson says that most organ procurement organizations now “shy away from the concept of selling organs as if you made an indecent proposal...they are afraid that the whole system might collapse.”

Not so, Kappel says. “Our organization has for a number of years been in favor of trying to do a pilot (compensation) program. We don’t know if the concept is good or bad, but we’ll never know if it works or not if we don’t try it under some controlled circumstances.”

Would a compensation system increase organ supply? Munson and Kappel say that study results are mixed. “Whether it would increase donation, I don’t know,” Kappel says. But he notes that others within the transplant system are compensated. “Everybody in the system gets paid. I get paid; my staff gets paid; surgeons get paid; hospitals get paid. You have to be careful that organs aren’t available to the highest bidder, but there can be some incentive.”

Kappel and others suggest reasonable compensation might take the form of helping families pay the funeral expenses associated with a death and subsequent cadaver organ donation opportunity.

“Once a month, we’re approached by a family member asking for assistance with funeral expenses,” Kappel says. “I don’t know what would be wrong with that.”

Martin D. Jendrisak, a transplant surgeon with Washington University School of Medicine, suggests that a so-called “presumed consent” law could be enacted to spur donations. Under such legislation, authorities would presume that a deceased person is a willing organ donor unless that person “opts out” by registering his or her opposition.

“In several countries people make it a community responsibility to support organ donation, and they have implied consent for donation,” Jendrisak says. “The rate of opting out is apparently under 10 percent, and these countries such as Denmark don’t see the degree of shortages we see in this country.”



“It’s not in the best interests of anyone to have organs sold on e-Bay.”

Ronald Munson
professor of science and
medicine philosophy,
University of Missouri–St. Louis

While Munson says presumed consent for organ donations is controversial and carries with it questions of due process and other constitutional issues, Jendrisak notes that states have the right to perform autopsies under certain conditions and over the objections of family members.

“Our best hope, though, is that we continue with broad public education beginning at the elementary and high school level and continuing through all phases of adult life,” Jendrisak believes.

To increase organ supply, Kappel suggests that area businesses help educate employees through various workplace initiatives for which MTS can provide assistance, such as informational payroll stuffers. Individuals, he adds, can obtain organ donor information through MTS. Once a decision to donate is made, potential donors should make their intentions known to family members and register their intent through the Missouri or Illinois Department of Revenue, both of which maintain a donor registry.


William V. Poe is principal of Poe Communications, a St. Louis advertising and marketing communications firm.
 

 

 


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