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A Regional Resource

The Siteman Cancer Center promises to provide the latest and greatest in cancer care.

By Peter Downs

Cancer care in St. Louis has moved into the big leagues. With a new facility for the Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine opening this month, and a new designation as a National Cancer Institute Cancer Center, “it is like moving from Division III to Division I in college athletics,” says Ron Evans, president of Barnes-Jewish Hospital.

The move was a long time in the making—26 years, according to Evans—but it is certain to have a big impact on both health care in the St. Louis region, and the region’s economic development.

NCI Endorsement

The designation from the National Cancer Institute (NCI) “means funds for us to become greater, for us to grow,” says William Peck, chancellor of the medical school. And, just as importantly, “it will allow us to provide the best, the latest, the most sensitive, and the most personal care...defining the state of the art in cancer care.”

Specifically, the NCI designation means the Siteman Cancer Center will get $4 million in NCI funds over three years, and patients will have access to the newest drugs and treatment regimens, which are only given to NCI-designated cancer centers for testing. Currently, “there are more than 250 clinical trials” of new anti-cancer agents available only through NCI cancer centers, says Dr. Timothy Eberlein, director of the Siteman Cancer Center, who was recruited from the famed Harvard Medical School, where he was the Richard E. Wilson Professor of Surgery. He also served as vice chairman for research in the Department of Surgery at Brigham and Women’s Hospital. Eberlein continues, “There also are genetic studies open only to NCI-designated centers as well.”

Already, the 235 doctors at Siteman see 5,000 new patients and 2,400 follow-up patients each year. They participate in 250 clinical trials, and are getting $85 million in research and training grants. Now, they’ll probably get even busier.

Although Siteman is the 61st NCI-designated cancer center, it is the only one in Missouri, and the only one within 240 miles of St. Louis. The closest neighboring NCI Cancer Centers are in West Lafayette and Indianapolis, Indiana; Iowa City; Omaha; Memphis; and two in Chicago, but the latter two “are much smaller,” Eberlein says. There are none in Arkansas, Kansas, Oklahoma or Kentucky.



Above: Timothy J. Eberlein, M.D., Director of the Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital.

Gwen Randall, a cancer patient who has had three bouts of breast cancer, five courses of chemotherapy and two courses of radiation, says “I take comfort in knowing that we have a facility like Siteman that is close to me.”

Eberlein expects the NCI-designation will bring more patients to Siteman, and more research. “We’ll probably see an increase in trials here, and in unique programs that attract interest from biotech and pharmaceutical investors. We’ll be like a Nidus for biomedicine” he says, likening Siteman to the business incubator Monsanto established for start-up plant science companies.

Together with the newly-opened Stowers Institute in Kansas City, Siteman’s NCI designation helps build Missouri’s growing reputation as a center for biomedical research.

The Stowers Institute for Medical Research opened on November 1, 2000, with an endowment of $550 million and a new $230 million research facility. Modeled after the Howard Hughes Medical Institute (HHMI), it will fund basic research into understanding how genes and proteins regulate life, but unlike HHMI, all the research will have to be performed onsite at its facility in Kansas City.

Siteman’s New Facility

The construction of a new $46 million cancer care facility for the Siteman Cancer Center was instrumental for getting the NCI’s support, but was not by itself enough to secure that support, Peck says.



Above: William A. Peck, M.D., executive vice chancellor for medical affairs and dean of the School of Medicine.

Facilities make-up one of the six essential organizational and administrative characteristics the NCI looks at in awarding its cancer center designation and grants. The others are: a clearly defined scientific focus on cancer research; a strong commitment of the parent institution to the cancer center; joint activities, collaborations and interactions within and among the different parts of the cancer center program; a full-time, or nearly full-time director who is a highly qualified scientist and administrator with the leadership experience and authority appropriate to the managing of a complex organization; and research activity in a variety of disciplines and a high degree of coordination, interaction and collaboration among cancer center members.

Where the new facility will have a significant impact, Eberlein says, “is on the way we deliver care.” Specifically, the new facility is both more welcoming to patients, and it encourages the kind of collaborative, multidisciplinary approach valued by the NCI.

“One of the criticisms of big academic medical centers is they’re very complex and very difficult for patients to find their way, it is very intimidating. Here we have consolidated 32 different places of interaction with patients into one building, built from patients’ points of view. Hopefully, we’ve made it easy to find and convenient. Parking is in a garage across the street; the bridge that brings you across the street ends at the Cancer Center information desk, and there is an elevator that only stops at the cancer floor.”

The Siteman Cancer Center occupies more than 107,000 square feet in the new Center for Advanced Medicine, including the lower level and the seventh floor. The lower level houses the radiation oncology center with eight linear accelerators used for radiation therapy and two advanced CT simulators. “All of our radiology will be totally digitalized,” Eberlein says. “Anything you have done within our facility or institution will be immediately available on computer, so doctors can blow it up, compare one x-ray with another, etc. It is a tremendous convenience that will allow for better patient care.”

The seventh floor houses outpatient services in modules designed both to facilitate a multidisciplinary team approach to care and for flexibility to accommodate changing health care needs.

Before, the approximately 150 physicians who provided care to cancer patients were spread all over in different areas, and each specialty was in a different place. “Medical oncology was on one part of the campus, surgical oncology on a different part,” Eberlein says. “If you were seeing three or four different doctors because of your particular problem, you could see me in one building, then go to a totally different building to see someone else, then go to another one to see a third doctor. Now, we will bring the doctors to you.”

In the new team approach, seeing multiple doctors will become the norm rather than the exception. A medical oncologist, a radiation oncologist, a surgical oncologist, and a psychologist and whatever other specialists are necessary will work together to develop a specific treatment plan for each individual patient. “We believe this will give better and more efficient cancer care,” Eberlein says.

It also will be friendlier care. “This is not a typical medical care delivery building,” Eberlein explains. “It is not a big, imposing, intimidating place. It is more like a Four Seasons Hotel with a big skylight and a pleasant, easy atmosphere.”

The development of the Siteman Cancer Center was made possible, in part, by a donation of $35 million from Alvin J. and Ruth Siteman in 1996. Existing, but physically separate anti-cancer efforts and doctors’ offices were then collectively renamed the Siteman Cancer Center, and work proceeded towards construction of a common facility and NCI designation.


Peter Downs is a free-lance writer and editor of Construction News & Review.
 

 

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