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Biotechnology

Seeding Growth

Research advances create a rosy future for region's life and plant sciences cluster.
By Kevin Kipp

It may be a conundrum to the technocrats of the European Union, but some St. Louisans know how to feed more people and consume fewer resources.

And it's a darn good thing, too, if--as Dr. William H. Danforth, chairman of the Donald Danforth Plant Science Center, avers in a January St. Louis Post-Dispatch op-ed--the world population is headed to 8 billion souls by 2025.

After quoting this and other World Health Organization predictions, he asked: How are we going to feed two billion--roughly eight times the United States' population--extra mouths?

Not to mention that presumably there's life--and more babies--after 2025.

"To protect agriculture for the long term," Roger Beachy, Ph.D., president of the Donald Danforth Plant Science Center says in an interview, "we need to make it is as clean and sustainable as we can possibly make it." We need to reduce damage to air, soil, and water from agricultural chemicals.

Again, how?

Dr. Danforth's piece went on to suggest that erosion is an even more immediate concern for agriculture. Worldwide, the annual loss of topsoil is equivalent to ALL of it in Missouri. How can we improve the sustainability of farming practices?

Seeding Growth

Drs. Danforth and Beachy suggest a solution. Fellows in research at the Missouri Botanical Garden say the solution will work. University professors, corporate scientists, and others tied to the St. Louis plant science and agriculture economy agree.

They believe the answer lies in plant and life sciences--including research on the effects of molecular and genetic changes in cells--to discover how to safely produce desirable characteristics in plants: increased yields, drought tolerance, pest resistance and improved nutrition.

Consider the potential:

  • Genetic modifications can increase yields. We've pursued this end since discovering that cultivating the grasses with the largest seeds meant we could eat better than relying exclusively on hunting and gathering. (Where do you city slickers think wheat comes from, anyway?)
  • Genetic modifications can add nutrition. For instance, a new strain of rice holds the promise of reducing blindness among children in Third World economies by improving the absorption of Vitamin A.

  • Genetic modifications can make plants resistant to pests, thus reducing dependence on chemical applications. Dr. Beachy: "Minimizing the use of chemicals to control weeds and pests limits overspray into wind rows and wood lots."

Wait a minute, cry Europe's trade delegates and some Green Yanks, too: You might create an herbaceous Frankenstein or bacterial nightmare.

Beachy grants that step one on the way to market should be, and is, to question our new technology.

"Step two," he says, "is to accept or reject the new technology based on scientific evaluation and safety to the environment. And "safe, compared to what?" he asks, "to what already exists? Or to an unattainable ideal?

"Our role is to assess scientific validity related, in this case, to foods that come from biotechnology," he says. "Scientists do that best by using scientific principles and sharing their results with the public."

As scientists and researchers in the St. Louis region continue to uncover safe solutions for tough problems facing agriculture and the environment, they are also uncovering an enormous opportunity. With purposeful positioning, the reasoning goes, the region can leap forward as the world center of world-class research and world-beating technologies in plant and life sciences.

(For an excellent look at how we've responded to plant and life science opportunities thus far, see Liese Hutchison's cover story in the October 1999 issue of St. Louis Commerce.)

Seeding Growth

To that end, and to add insight, the RCGA asked Battelle Memorial Institute, the world's largest non-profit research and development organization, to help area leaders generate a regional strategic plan.

Walter Plosila, Battelle's vice president of public technology management, has started with a SWOT analysis: Strength, Weakness, Opportunity, Threat. Plosila expects that a working technology partnership will link universities, private business and government.

Also, he says, the plan will outline "how to coordinate these and other crucial elements to support each other: work force, higher education partnerships, capital formation, technology infrastructure, research parks, incubators, accelerators, smart buildings and the business climate, taxes, regulations, image and entrepreneurship."

And the Battelle plan will identify gaps in the research-to-markets continuum, benchmarks of best practices, identification of core research strengths.

Our work will ensure that the St. Louis region will have a strong plant and life science base that can respond to the ebbs and flows of the economy," he notes.

Whatever Plosila and Battelle might find lacking, they will likely laud the Nidus Center for Scientific Enterprise. It's an incubator for companies involved in some facet of life science--whether plant, animal or medical.

Located on Monsanto's campus and primarily funded by Monsanto, the 41,000-square-foot building has the capacity to house 13 to 15 companies, according to Nidus president and CEO Robert Calcaterra.

The building--besides being adequately environmentally sound to probably earn a U.S. Green Council award--has laboratories and offices, as well as what Calcaterra calls "growth chambers designed especially for ag and research work."

Less than a month and a half after opening, the center had its first tenant. But Calcaterra estimated that "in five or six years, our companies [in-house and alumni] could be generating a quarter of a billion dollars in annual revenue."

It's not just the Nidus companies, Monsanto or the region's other plant and life science institutions that could be adversely affected by Europe's Luddite-like hysteria.

Beachy points out that plant science research funding is a small portion of life sciences research; he estimated 2 to 5 percent. Furthermore, this sliver of funding is stretched even farther because "sponsored research generally includes research AND development of a prototype," he says.

"We don't want the current environment in Europe to impact biotechnology research in this country," Dr. Beachy says. "If Congress cuts research funding...we're so underfunded already that any cuts would be devastating to the future. In contrast, we should respond with more research and information to help our friends at home and abroad to accept or reject the technologies on their scientific merits."

For its part, Battelle's planning won't address the European Union's concerns. Plosila says, "Our problem isn't to solve the agricultural biotech issues of the globe. It's to help the RCGA position St. Louis to be competitive in plant and life sciences, whatever happens globally.

Instead, Plosila asks: "Do the various assets work effectively to create high-paying jobs in St. Louis?"


Kevin Kipp runs Bubble Communications, a creative services and community relations firm in St. Charles.

 

 

 

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